Association of Multidrug-Resistant Tuberculosis (MDR-TB) Patients on Profile of Liver and Kidney Function

Authors

DOI:

https://doi.org/10.30872/j.kes.pasmi.kal.v5i2.9640

Abstract

Introduction: Therapy of multidrug-resistant tuberculosis (MDR-TB) patients is still not handled properly, is more toxic, and is more high-priced. The liver is the primary metabolism, and the kidney is the main excretion organ. The study aims to know the association of multidrug-resistant tuberculosis (MDR-TB) patients on profile of liver and kidney function Methods: The research is a cross-sectional study with consecutive sampling. Twenty-four respondents were confirmed as MDR-TB patients without HIV who had done biochemical tests. Results: We found that sex of MDR-TB patients on liver function; ALT (p = 0.124) and AST (p = 0.077) and kidney function; BUN (p = 0.270), creatinine (p = 0.137).  Age of MDR-TB patients on liver function; ALT (p = 0.587) and AST (p = 0.093) and kidney function; BUN (p = 0.423), creatinine (p = 0.142). Comorbid on MDR-TB patients on liver function; ALT (p = 0.756) and AST (p = 0.244) and kidney function; BUN (p = 0.816), creatinine (p = 0.612). Conclusions: There were no association in sex, age, and comorbid of MDR-TB on liver and kidney function.

Author Biographies

  • Iskandar Muda, Mulawarman University

    Laboratory of Biomedicine, Diploma of Nursing Program, Faculty of Medicine

  • Muhammad Fadlan Adam, Mulawarman University
    Medical Doctor Program, Faculty of Medicine
  • Rudi Saputra, Mulawarman University
    Medical Study Program, Faculty of Medicine
  • Annisa Muhyi, Mulawarman University
    Laboratory of Pediatrics, Faculty of Medicine
  • Dwi Noprianto, Mulawarman University
    Laboratory of Fundamental Nursing, Diploma of Nursing Program, Faculty of Medicine
  • Muhammmad Aminuddin, Mulawarman University

    Laboratory of Biomedicine, Diploma of Nursing Program, Faculty of Medicine

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Published

2023-02-05

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Vol. 5 No. 2 (2022): JKPBK Desember 2022

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Articles

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