The Relationship between Hypertension and Dyslipidemia with Degree of Coronary Stenosis in Patients with Coronary Artery Disease at Abdoel Wahab Sjahranie Hospital in Samarinda
Abstract
Coronary Heart Disease or Coronary Artery Diseae (CAD) is the leading cause of death in worldwide, including in Indonesia. CAD is caused by blockage of the coronary arteries, which a coronary angiography examination can confirm to assess the degree of stenosis. Hypertension and dyslipidemia are the main risk factors in patients with CAD. This study aims to analyze the relationship between hypertension and dyslipidemia with the degree of coronary stenosis in patients with CAD who undergo angiography at Abdoel Wahab Sjahranie Samarinda Hospital. This study is a type of analytic observational research with a cross-sectional approach. The data used in this study was from medical records. The study sample was 93 patients with CAD who underwent angiography at Abdoel Wahab Sjahranie Samarinda Hospital in 2022 and met the inclusion and exclusion criteria selected by purposive sampling. The result showed that the relationship between hypertension and the degree of coronary stenosis showed a p-value of 0.632 and a p-value of 0,034 for the relationship between dyslipidemia and the degree of coronary stenosis. The conclusion of this study is that hypertension has no relasionship with the degree of coronary stenosis and dyslipidemia has a significant relationship with the degree of coronary stenosis in patients with CAD who undergo angiography.
Keywords: Coronary Artery Disease, Hypertension, Dyslipidemia, Degree of Coronary Stenosis, Angiography
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Shahjehan RD, Bhutta BS. Coronary Artery Disease. In Treasure Island (FL); 2023.
American Heart Association. 2022 Heart Disease & Stroke Statistical Update Fact Sheet Global Burden of Disease High Blood Cholesterol and Other Lipids. 2022;(CVD):9–11.
Kementerian Kesehatan RI. Riset Kesehatan Dasar (Riskesdas) [Internet]. Jakarta: Badan Penelitian dan Pengembangan Kesehatan; 2013. Available from: https://dinkes.bantenprov.go.id/upload/article_doc/Hasil_Riskesdas_2013.pdf
Lilly LS. Pathophysiology of Heart Disease: a collaborative project of medical students and faculty. 6th ed. Philadelphia: Wolters Kluwer; 2016. 115–153 p.
Brown JC, Gerhardt TE, Kwon E. Risk Factors For Coronary Artery Disease. In Treasure Island (FL); 2023.
Alyssia N, Noormartany, Amalia N. Scooping Review : Pengaruh Hipertensi terhadap Penyakit Jantung Koroner. Pros Pendidik Kedokt [Internet]. 2020;7(1):127–32. Available from: https://karyailmiah.unisba.ac.id/index.php/dokter/article/download/26491/pdf
Amisi WG, Nelwan JE, Kolibu FK. Hubungan antara Hipertensi dengan Kejadian Penyakit Jantung Koroner pada Pasien yang Berobat di Rumah Sakit Umum Pusat Prof. Dr. R. D. Kandou Manado. Kesmas. 2018;7(4):1–7.
Eliyani ND, Hartopo AB, Anggraeni VY. HUBUNGAN ANTARA HIPERTENSI DENGAN KEPARAHAN LESI ARTERI KORONER PADA PASIEN YANG MENJALANI ANGIOGRAFI KORONER. Univ Gadjah Mada [Internet]. 2019; Available from: http://etd.repository.ugm.ac.id/
Husni M, Lapau B, Hardhana B. Hubungan Dislipidemia dan Diabetes Mellitus dengan Kejadian Penyakit Jantung Koroner Di RSUD. Caring Nurs J. 2018;2(2):66–9.
Perkumpulan Endokrinologi Indonesia. Pedoman Pengelolaan Dislipidemi di Indonesia. PB. Perkeni. 2019.
Abduh MS, Triono MR. Analisis Profil Lipid Sebagai Prediktor Keparahan Stenosis Coronary Artery Disease yang Dinilai Menggunakan Gensini Score. J Wiyata [Internet]. 2022;09:79–87. Available from: http://dx.doi.org/10.56710/wiyata.v9i2.603
Ramadhani RA. HUBUNGAN KADAR KOLESTEROL TOTAL DENGAN DERAJAT STENOSIS BERDASARKAN GENSINI SCORE (Studi Observasional pada Pasien Penyakit Jantung Koroner di RSI Sultan Agung Semarang). Univ Islam Sultan Agung [Internet]. 2019; Available from: http://repository.unissula.ac.id/14067/
Widyawati DG, Yasmin A. ADA, Gunadhi IP. Hubungan antara profil lipid dengan derajat stenosis arteri koroner pada pasien penyakit jantung koroner stabil. Medicina (B Aires) [Internet]. 2021;52(2):132–6. Available from: https://medicinaudayana.ejournals.ca/index.php/medicina/article/view/682%0Ahttps://medicinaudayana.ejournals.ca/index.php/medicina/article/download/682/441
Wangko LC, Budiono B, Lefrandt RL. Angiografi Koroner Indikasi, Kontraindikasi, Dan Proteksi Terhadap Radiasi. J Biomedik. 2013;4(3):150–5.
Herscovici R, Sedlak T, Wei J, Pepine CJ, Handberg E, Bairey Merz CN. Ischemia and No Obstructive Coronary Artery Disease (INOCA): What Is the Risk? J Am Heart Assoc [Internet]. 2018 Sep 4;7(17):e008868. Available from: https://doi.org/10.1161/JAHA.118.008868
Xu Z, Pan J, Chen T, Zhou Q, Wang Q, Cao H, et al. A prediction score for significant coronary artery disease in Chinese patients ≥50 years old referred for rheumatic valvular heart disease surgery. Interact Cardiovasc Thorac Surg [Internet]. 2018 Apr 1;26(4):623–30. Available from: https://doi.org/10.1093/icvts/ivx408
Azahra AN, Akbar MR, Rathomi HS. Hubungan Antara Faktor Risiko Klasik Penyakit Arteri Koroner Dan Derajat Stenosis Arteri Koroner Pada Pasien Infark Miokard Akut Di Rsup Dr. Hasan Sadikin Bandung Periode 2017-2018. Univ Islam Bandung Repos [Internet]. 2020; Available from: http://repository.unisba.ac.id/handle/123456789/30504
Nakanishi R, Baskaran L, Gransar H, Budoff MJ, Achenbach S, Al-Mallah M, et al. Relationship of Hypertension to Coronary Atherosclerosis and Cardiac Events in Patients with Coronary Computed Tomographic Angiography. Hypertension. 2017;70(2):293–9.
Berge CA, Eskerud I, Almeland EB, Larsen TH, Pedersen ER, Rotevatn S, et al. Relationship between hypertension and non-obstructive coronary artery disease in chronic coronary syndrome (the NORIC registry). PLoS One [Internet]. 2022 Jan 21;17(1):e0262290. Available from: https://doi.org/10.1371/journal.pone.0262290
Price SA, Wilson LM. Patofisiologi: Konsep Klinis Proses-Proses Penyakit. 6th ed. Jakarta: Penerbit Buku Kedokteran EGC; 2015.
Khalid K, Padda J, Ismail D, Abdullah M, Gupta D, Pradeep R, et al. Correlation of Coronary Artery Disease and Left Ventricular Hypertrophy. Cureus. 2021 Aug;13(8):e17550.
Nahdah NO, Abduh MS, Sumarawati T. Hubungan Atherosclerotic Cardiovascular Disease Score dengan derajat stenosis berdasarkan gensini score. J Ilm Sultan Agung. 2023;1178–86.
Khashayar P, Mohagheghi A. The correlation between dyslipidemia and coronary artery disease based on angiographic findings in an Iranian population. Acta Med Indones. 2010 Apr;42(2):82–5.
Yulianti A, Wardani HP, Nurruhyuliawati W. Hubungan Kolesterol Low Density Lipoprotein dengan Derajat Stenosis Arteri Koroner pada Pasien Penyakit Arteri Koroner di Rumah Sakit Al Islam Bandung Tahun 2017-2018. Pros Kedokt [Internet]. 2020;6(1):253–8. Available from: http://repository.unisba.ac.id/handle/123456789/27417
Mahalle N, Garg MK, Naik SS, Kulkarni M V. Study of pattern of dyslipidemia and its correlation with cardiovascular risk factors in patients with proven coronary artery disease. Indian J Endocrinol Metab. 2014 Jan;18(1):48–55.
Berberich AJ, Hegele RA. A Modern Approach to Dyslipidemia. Endocr Rev. 2022;43(4):611–53.
Zhao X, Wang D, Qin L. Lipid profile and prognosis in patients with coronary heart disease: a meta-analysis of prospective cohort studies. BMC Cardiovasc Disord [Internet]. 2021;21(1):69. Available from: https://doi.org/10.1186/s12872-020-01835-0
Mihăilă R-G. Pragmatic Analysis of Dyslipidemia Involvement in Coronary Artery Disease: A Narrative Review. Curr Cardiol Rev. 2020;16(1):36–47.
DOI: http://dx.doi.org/10.30872/j.kes.pasmi.kal.v8i1.12786
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